Reported by ClinVar to cause familial temporal lobe epilepsy (https://www.ncbi.nlm.nih.gov/clinvar/variation/208481/). In ClinVar this variant is reported as “pathogenic” (causing this condition) by a single source, GeneReviews, which cites their article written by Ruth Ottman: https://www.ncbi.nlm.nih.gov/books/NBK1537/
This variant is somewhat rare according to ExAC data, potentially consistent with the reported disease-causing hypothesis (http://exac.broadinstitute.org/variant/7-103281044-G-A).