IL23R G149R - GET-Evidence

Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.

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IL23R G149R

(IL23R Gly149Arg)

You are viewing the latest version of this page, saved on April 12, 2017 at 10:07pm by Alana Lynch.

Edited in this revision:

Short summary

possibly associated with protection against inflammatory bowel disease

Variant evidence
Computational -
Functional -
Case/Control -
Familial -
Clinical importance
Severity -
Treatability -
Penetrance -


Insufficiently evaluated not reviewed

(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)

Inheritance pattern


Summary of published research, and additional commentary


Allele frequency

  • A @ chr1:67648596: 0.3% (35/10758) in EVS
  • Frequency shown in summary reports: 0.3% (35/10758)


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PubMed PMID: 26887945




Other external references

  • rs76418789
  • Score: 0.998 (probably damaging)
    Web search results (0 hits -- see all)

Other in silico analyses

  • NBLOSUM100 score = 6
  • GET-Evidence autoscore = 2

Edit history

Gene search

"GENE" or "GENE A123C":

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