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Seen in 10 out of 526 DCM cases with European ethnic origin, and not seen in 320 age-matched European controls. The authors report this as “P < 0.01 by exact Fisher test”, but we calculate it to be p = 0.016 using a two-tailed Fisher’s Exact test.
Cases/controls | case+ | case– | control+ | control– | p-value | odds ratio |
Dilated Cardiomyopathy
| 10 |
516 |
0 |
320 |
0.0164 |
∞ |
Testing 652 DCM and 354 HCM patients, and 1066 chromosomes of control probands (= 533 individuals) this variant was seen in 3 DCM cases, 2 HCM, and 2 controls.
Cases/controls | case+ | case– | control+ | control– | p-value | odds ratio |
Dilated Cardiomyopathy
| 3 |
649 |
2 |
531 |
1.0000 |
1.227 |