Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.
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Insufficiently evaluated pathogenic
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Summary of published research, and additional commentary
Dahlman KB, Xia J, Hutchinson K, Ng C, Hucks D, Jia P, Atefi M, Su Z, Branch
S, Lyle P, Hicks DJ, Bozon V, Glaspy JA, Rosen N, Solit DB, Netterville JL,
Vnencak-Jones CL, Sosman JA, Ribas A, Zhao Z, Pao W. BRAF L597 mutations in
melanoma are associated with sensitivity to MEK inhibitors. Cancer Discov. 2012
Jul 13. [Epub ahead of print] PubMed PMID: 22798288.