A survey of WDR36 mutations to look for association with glaucome. This variant was seen in 4 out of 399 patients and 11 out of 376 controls. This is evidence against any pathogenic effect and, if anything, weak evidence supporting a slightly protective effect.
Functional testing of equivalent substitution in yeast shows no growth defects (table 1). The authors interpret this variant as non-pathogenic based on its presence in controls.