TLR6 S249P - GET-Evidence

Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.

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TLR6 S249P

(TLR6 Ser249Pro)

You are viewing an old version of this page that was saved on December 27, 2009 at 4:05pm by Genome Importing Robot.

Added in this revision:

Short summary


Variant evidence
Computational -
Functional -
Case/Control -
Familial -
Clinical importance
Severity -
Treatability -
Penetrance -


Insufficiently evaluated not reviewed

(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)

Inheritance pattern


Summary of published research, and additional commentary


Allele frequency

  • G @ chr4:38830350: 69.5% (7479/10758) in EVS
  • G @ chr4:38506744: 85.2% (109/128) in GET-Evidence
  • Frequency shown in summary reports: 69.5% (7479/10758)



Other external references

  • [Malaria]
    This study suggests that the TLR6 249S allele may be a risk factor for malaria.
  • Score: 0 (benign)

Other in silico analyses

  • NBLOSUM100 score = 3
  • GET-Evidence autoscore = 1

Edit history

Gene search

"GENE" or "GENE A123C":

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