SCRN2 K103R - GET-Evidence

Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.

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(SCRN2 Lys103Arg)

Short summary


Variant evidence
Computational -
Functional -
Case/Control -
Familial -
Clinical importance
Severity -
Treatability -
Penetrance -


Insufficiently evaluated not reviewed

(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)

Inheritance pattern


Summary of published research, and additional commentary


Allele frequency

  • C @ chr17:45917605: 2.8% (306/10758) in EVS
  • C @ chr17:43272603: 0.8% (1/128) in GET-Evidence
  • Frequency shown in summary reports: 2.8% (306/10758)




huE80E3D - CGI sample GS00253-DNA_D01_200_37
het C @ chr17:45917605


Other external references

  • rs17856536
    Web search results (4 hits -- see all)
  • SCRN2 Gene - GeneCards | SCRN2 Protein | SCRN2 Antibody
    SCRN2 Gene in genomic location: bands according to Ensembl, locations according to (and ... Monoclonal and Polyclonal Antibodies from Abnova (SCRN2) ...
  • A Functional Polymorphism under Positive Evolutionary ...
    Selection in ADRB2 is Associated with Human Intelligence. with Opposite Effects in the ... SCRN2. rs17856536. Derived. G. Unknown. Arg [R] 103. Ancestral. A. Unknown ... (2009) Behav Geneti...
  • Secernin-2 - Homo sapiens (Human)
    SCRN2. Organism. Homo sapiens (Human) [Complete proteome] Taxonomic identifier. 9606 [NCBI] ... K R: dbSNP rs17856536. Ref.3. VAR_029509. Natural variant. 273. 1. E Q: ...

Other in silico analyses

  • NBLOSUM100 score = –3
  • GET-Evidence autoscore = 2

Edit history

Gene search

"GENE" or "GENE A123C":

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