IQGAP2 V455A - GET-Evidence

Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.

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(IQGAP2 Val455Ala)

Short summary


Variant evidence
Computational -
Functional -
Case/Control -
Familial -
Clinical importance
Severity -
Treatability -
Penetrance -


Insufficiently evaluated not reviewed

(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)

Inheritance pattern


Summary of published research, and additional commentary


Allele frequency

  • C @ chr5:75906851: 4.9% (524/10758) in EVS
  • C @ chr5:75942606: 3.1% (4/128) in GET-Evidence
  • Frequency shown in summary reports: 4.9% (524/10758)






GS18555 - var-GS18555-1100-36-ASM
het C @ chr5:75942607


GS18940 - var-GS18940-1100-36-ASM
het C @ chr5:75942607


GS21767 - var-GS21767-1100-36-ASM
het C @ chr5:75942607


Other external references

  • rs7722711
    Web search results (3 hits -- see all)
  • IQGAP2 Gene - GeneCards | IQGA2 Protein | IQGA2 Antibody
    IQGAP2 Gene in genomic location: bands according to Ensembl, locations according ... for IQGAP2. R&D Systems Antibodies for IQGAP2 (IQGAP2, IQGAP1) ...
  • Ras GTPase-activating-like protein IQGAP2 - Homo sapiens (Human)
    ... GTPase-activating-like protein IQGAP2 OS=Homo sapiens GN=IQGAP2 PE=1 SV=4 ... like protein IQGAP2. Gene names. Name: IQGAP2. Organism. Homo sapiens ...
    ... Ras GTPase-activating-like protein IQGAP2; GN Name=IQGAP2; OS Homo sapiens (Human). OC ... activating-protein-related human protein IQGAP2 RT harbors a potential actin binding ...

Other in silico analyses

  • NBLOSUM100 score = 2
  • GET-Evidence autoscore = 2

Edit history

Gene search

"GENE" or "GENE A123C":

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