IL17F V155I - GET-Evidence

Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.

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IL17F V155I

(IL17F Val155Ile)

Short summary


Variant evidence
Computational -
Functional -
Case/Control -
Familial -
Clinical importance
Severity -
Treatability -
Penetrance -


Insufficiently evaluated not reviewed

(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)

Inheritance pattern


Summary of published research, and additional commentary


Allele frequency

  • T @ chr6:52101758: 3.1% (330/10758) in EVS
  • T @ chr6:52209716: 3.9% (5/128) in GET-Evidence
  • Frequency shown in summary reports: 3.1% (330/10758)





huBEDA0B - CGI sample GS00253-DNA_C01_200_37
het T @ chr6:52101758



GS06985 - var-GS06985-1100-36-ASM
het T @ chr6:52209717


Other external references

  • rs11465553
  • Score: 0.564 (possibly damaging)
    Web search results (7 hits -- see all)
  • IL17F Gene - GeneCards | IL17F Protein | IL17F Antibody
    Sigma-Aldrich Antibodies for IL17F. R&D Systems Antibodies for IL17F (IL-17F) Search for ... Abnova (IL17F) Novus Biologicals Antibodies for IL17F. Browse ...
  • Association analysis of the interleukin 17 genes IL17A and ...
    ... six remaining SNPs, two were non‐synonymous (rs11465553 and rs2397084) ... IL17F as potential osteoarthrit...Association analysis of the interleukin 17 genes IL17A and IL17F as ...
  • Interleukin-17F precursor - Homo sapiens (Human)
    IL17F. Synonyms: IL24. Organism. Homo sapiens (Human) [Complete proteome] ... V I: dbSNP rs11465553. VAR_058288. Natural variant. 161. 1. H R: dbSNP rs763780. Ref.3 ...
  • SNP Dataset 4 (xls 2034K) - Nature Publishing Group : science ...
    IL17F. 6. 52209443. 52217257. 40. 469. rs612242. C/G. intron/UTR. 470. rs721430 ... rs11465553. A/G. non-synonimous. 500. rs11465554. A/G. intron/UTR. 501. rs12182710. C/T. intron/UTR ...
  • A Multiplex Human Syndrome Implicates a Key Role for ...
    Piya Lahiry, Jian Wang, John F. Robinson, Jacob P. Turowec, David W. Litchfield, ... rs11465553 CAT-H; CGT-R; H161R; probably damaging. U:AA, A:AA, C:AA, ...
  • UniProt: IL17F_HUMAN
    AC Q96PD4; Q6NSI0; Q7Z6P4; Q96PI8; Q9NUE6; DT 31-JAN-2002, integrated ... GeneCards; GC06M052209; -. DR H-InvDB; HIX0032794; -. DR HGNC; HGNC:16404; IL17F. ...

Other in silico analyses

  • NBLOSUM100 score = –4
  • GET-Evidence autoscore = 2

Edit history

Gene search

"GENE" or "GENE A123C":

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