Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.
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PolyPhen2: Possibly damaging 0.993
SIFT: Affect protein function 0.00
GVGD: Class C65
Insufficiently evaluated not reviewed
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Summary of published research, and additional commentary
hu728FFF - PGP11 (hu728FFF) build 36, substitution variants
hom A @ chr22:25184441