Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.
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(FPR1 Ile11Thr)
You are viewing an old version of this page that was saved on March 29, 2011 at 8:55pm by Genome Importing Robot.
Short summary
Impact
Insufficiently evaluated pharmacogenetic
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Inheritance pattern
unknown
Summary of published research, and additional commentary
Bhattacharya M, Wang J, Ribeiro FM, Dixon SJ, Feldman RD, Hegele RA, Ferguson SS. Analysis of a missense variant of the human N-formyl peptide receptor that is associated with agonist-independent beta-arrestin association and indices of inflammation. Pharmacogenomics J. 2007 Jun;7(3):190-9. Epub 2006 Sep 5. PubMed PMID: 16953235.
Benachour H, Zaiou M, Herbeth B, Lambert D, Lamont JV, Pfister M, Siest G, Tiret L, Blankenberg S, Fitzgerald PS, Visvikis-Siest S. Human formyl peptide receptor 1 (FPR1) c.32C>T SNP is associated with decreased soluble E-selectin levels. Pharmacogenomics. 2009 Jun;10(6):951-9. PubMed PMID: 19530962.
hu034DB1 - CGI sample GS00253-DNA_A02_200_37 hom G @ chr19:52250216
hu04FD18 - CGI sample GS00253-DNA_F01_200_37 hom G @ chr19:52250216
hu0D879F - CGI sample GS00253-DNA_G01_200_37 het G @ chr19:52250216
hu3215A7 - PGP12 (hu3215A7) build 36, substitution variants, hu3215A7 build 36 substitution variants hom G @ chr19:56942028
hu43860C - CGI sample GS00253-DNA_A01_200_37 het G @ chr19:52250216
hu728FFF - PGP11 (hu728FFF) build 36, substitution variants, hu728FFF build 36 substitution variants het G @ chr19:56942028
hu9385BA - CGI sample GS00253-DNA_E01_200_37 het G @ chr19:52250216
huAE6220 - CGI sample GS00253-DNA_H01_200_37 het G @ chr19:52250216
huBEDA0B - CGI sample GS00253-DNA_C01_200_37 het G @ chr19:52250216
huC30901 - CGI sample GS00253-DNA_B01_200_37 het G @ chr19:52250216
huE80E3D - CGI sample GS00253-DNA_D01_200_37 hom G @ chr19:52250216
GS07357 - var-GS07357-1100-36-ASM het G @ chr19:56942028
GS12004 - var-GS12004-1100-36-ASM het G @ chr19:56942028
Added in this revision:
GS18501 - var-GS18501-1100-36-ASM hom G @ chr19:56942028
GS18502 - var-GS18502-1100-36-ASM hom G @ chr19:56942028
GS18504 - var-GS18504-1100-36-ASM hom G @ chr19:56942028
GS18505 - var-GS18505-1100-36-ASM hom G @ chr19:56942028
NA07022
NA12156
NA12878
NA18507
NA18517
NA18555
NA18956
NA19129
NA19240
snp-1
snp-18
snp-2
snp-27
snp-28
snp-29
snp-3
snp-30
snp-31
snp-6