FGA T312A - GET-Evidence

Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.

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(FGA Thr312Ala)

Short summary


Variant evidence
Computational -
Functional -
Case/Control -
Familial -
Clinical importance
Severity -
Treatability -
Penetrance -


Insufficiently evaluated pathogenic

(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)

Inheritance pattern


Summary of published research, and additional commentary


Allele frequency

  • None available.



Other external references

    Web search results (8 hits -- see all)
  • The metabolic syndrome is a complex disease which is characteri
    AGTR1/A1166C, ACE/ID and FGA/T312A in its development. Arsen Batagov ... the 3`-UTR and fibrinogen chain alpha (FGA) – an SNP leading. to a single aminoacid ...
  • ICSB 2007 :: Posters by Author
    A systems analysis of metabolic syndrome in human and the role of gene polymorphisms AGTR1/A1166C, ACE/ID and FGA/T312A in its development ...
  • Blood -- High prevalence of dysfibrinogenemia among patients ...
    Exons contained within the fibrinogen genes FGA, FGB, and FGG (encoding the A, B ... In addition to the T312A polymorphism, DNA sequence analysis disclosed a ...
  • OMIM: 134820
    The R16C mutation of the FGA gene is a common cause of dysfibrinogenemia and is ... in the FGA gene, resulting in a thr312-to-ala (T312A) substitution, and the development ...
  • Blood -- High prevalence of dysfibrinogenemia among patients ...
    Email this article to a friend. Alert me to new issues of the journal ... disclosed the common heterozygous Aα T312A polymorphism (not shown) and a second ...
  • [全文转载]都市科幻《双脑》作者:理想年代 @ 『 E书天下 』
    电子E书推荐、欣赏、下载、点评. 雷傲极酷超级论坛 『 E书天下 』 [返回] 浏览:[全文转载]都市科幻《双脑》作者 ... 标记论坛所有内容为已读. 目前论坛总在线 314 人,本主题共有 1 人浏览。 其中注册用户 0 人,访客 1 人。 [ 关闭详细列表] 此帖被阅读 6496 次 ...

Other in silico analyses

  • NBLOSUM100 score = 1
  • GET-Evidence autoscore = 4

Edit history

Gene search

"GENE" or "GENE A123C":

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