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Associated with cardiac toxicity with trastuzumab.
Insufficiently evaluated pharmacogenetic
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Summary of published research, and additional commentary
Matsuzawa D, Hashimoto K, Miyatake R, Shirayama Y, Shimizu E, Maeda K, Suzuki
Y, Mashimo Y, Sekine Y, Inada T, Ozaki N, Iwata N, Harano M, Komiyama T, Yamada
M, Sora I, Ujike H, Hata A, Sawa A, Iyo M. Identification of functional
polymorphisms in the promoter region of the human PICK1 gene and their
association with methamphetamine psychosis. Am J Psychiatry. 2007
Jul;164(7):1105-14. PubMed PMID: 17606663.
Added in this revision:
hu43860C - CGI sample GS00253-DNA_A01_200_37
het G @ chr17:37879588