A study in African American families found little correlation between S217L and prostate cancer (they note a p=0.03 difference in heterozygote sporadic cases). Sporadic cases: L/L: 3, S/L: 69, S/S: 83. Familial cases: L/L: 3, S/L: 30, S/L: 55. Controls: L/L: 15, S/L: 99, S/S: 182. Combined numbers with a recessive hypothesis is used below.