Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.
To be considered sufficiently evaluated a variant must have both "variant evidence" and "clinical importance" scores filled in.
Please help improve GET-Evidence by evaluating evidence for this variant!
(CYP2B6 Arg22Cys)
You are viewing the latest version of this page, saved on November 29, 2012 at 7:39am by Genome Importing Robot.
Short summary
Impact
Insufficiently evaluated pharmacogenetic
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Inheritance pattern
unknown
Summary of published research, and additional commentary
Rocha V, Porcher R, Fernandes JF, Filion A, Bittencourt H, Silva W Jr, Vilela G, Zanette DL, Ferry C, Larghero J, Devergie A, Ribaud P, Skvortsova Y, Tamouza R, Gluckman E, Socie G, Zago MA. Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia. Leukemia. 2009 Mar;23(3):545-56. Epub 2008 Nov 13. PubMed PMID: 19005482.
hu43860C - CGI sample GS00253-DNA_A01_200_37 het T @ chr19:41497274
Added in this revision:
huFFAD87 - CGI sample GS01669-DNA_H05 from PGP sample 10971581 hom T @ chr19:41497274
GS18942 - var-GS18942-1100-36-ASM het T @ chr19:46189114
GS19020 - var-GS19020-1100-36-ASM het T @ chr19:46189114
GS19025 - var-GS19025-1100-36-ASM het T @ chr19:46189114
GS19703 - var-GS19703-1100-36-ASM het T @ chr19:46189114