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Insufficiently evaluated pathogenic
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Summary of published research, and additional commentary
Green SA, Cole G, Jacinto M, Innis M, Liggett SB. A polymorphism of the human
beta 2-adrenergic receptor within the fourth transmembrane domain alters ligand
binding and functional properties of the receptor. J Biol Chem. 1993 Nov
5;268(31):23116-21. PubMed PMID: 7901205.
Added in this revision:
Brodde OE. Beta1- and beta2-adrenoceptor polymorphisms and cardiovascular
diseases. Fundam Clin Pharmacol. 2008 Apr;22(2):107-25. Review. PubMed PMID:
hu9385BA - CGI sample GS00253-DNA_E01_200_37
het T @ chr5:148206885