Note: This variant has not been sufficiently evaluated by a GET-Evidence editor.
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Insufficiently evaluated not reviewed
(The "insufficiently evaluated" qualifier is assigned automatically based on the above evidence and importance scores.)
Summary of published research, and additional commentary
Added in this revision:
Dishy V, Sofowora GG, Xie HG, Kim RB, Byrne DW, Stein CM, Wood AJ. The effect
of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated
vascular desensitization. N Engl J Med. 2001 Oct 4;345(14):1030-5. PubMed PMID:
Israel E, Chinchilli VM, Ford JG, Boushey HA, Cherniack R, Craig TJ, Deykin A,
Fagan JK, Fahy JV, Fish J, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF Jr,
Liggett SB, Martin RJ, Mitra N, Peters SP, Silverman E, Sorkness CA, Szefler SJ,
Wechsler ME, Weiss ST, Drazen JM; National Heart, Lung, and Blood Institute's
Asthma Clinical Research Network. Use of regularly scheduled albuterol treatment
in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial.
Lancet. 2004 Oct 23-29;364(9444):1505-12. PubMed PMID: 15500895.
Pacanowski MA, Gong Y, Cooper-Dehoff RM, Schork NJ, Shriver MD, Langaee TY,
Pepine CJ, Johnson JA; INVEST Investigators. beta-adrenergic receptor gene
polymorphisms and beta-blocker treatment outcomes in hypertension. Clin Pharmacol
Ther. 2008 Dec;84(6):715-21. Epub 2008 Jul 9. PubMed PMID: 18615004; PubMed
Central PMCID: PMC2675574.
hu034DB1 - CGI sample GS00253-DNA_A02_200_37
het A @ chr5:148206440